Abstract: Objective To investigate the effects of intraoperative blood salvage and allogeneic blood transfusion on liver function and plasma protein indexes in patients undergoing cesarean delivery. Methods A total of 100 patients undergoing cesarean delivery from February, 2017 to October, 2018 were enrolled in the retrospective study. The patients were divided into autologous transfusion group (interoperative blood salvage, n=50) and allogeneic transfusion group. (allogeneic blood transfusion, n=50). General clinical data, liver function indicators [alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP)] and plasma protein [total protein (TP), Albumin (Alb), globulin (Glo)] before and after surgery in the two-group patients were compared. Correlation and linear regression analysis were used to test correlation of the intraoperative autologous blood transfusion volume with intraoperative blood loss, postoperative liver function index, plasma protein index. Results There was no significant difference in clinical general data between the two groups (P>0.05). The amount of allogeneic blood was significantly lower in the autologous transfusion group than that in the allogeneic transfusion group (P<0.05). There was no significant difference between the average hospital stay and the 1 min neonatal score in the two groups. Compared with the preoperative, the ALP, TP, Alb and Glo of the two groups were significantly different (P<0.05), but ALT, AST changes were not obvious (P>0.05); there was no significant difference in postoperative indexes between the two groups (P>0.05); there was a significantly negatively correlation between ALP, TP, Glo and intraoperative autologous blood transfusion volume e (P<0.05). Conclusion Intraoperative blood salvage is a safe and effective way to save allogeneic blood. It is worthy of clinical promotion since Intraoperative blood salvage does not cause liver function damage and allogeneic immune response in patients with cesarean delivery.

Key words: Intraoperative cell salvage, Cesarean delivery, Plasma protein, Liver function, Immune response