Massive Fetomaternal Hemorrhage Caused by Maternal-fetal Blood Type Inconsistency:Diagnostic Value of Capillary Centrifugation

doi:10.3969/j.issn.1671-2587.2022.05.006

JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2022, Vol. 24 ›› Issue (5): 582-587.DOI: 10.3969/j.issn.1671-2587.2022.05.006

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Massive Fetomaternal Hemorrhage Caused by Maternal-fetal Blood Type Inconsistency:Diagnostic Value of Capillary Centrifugation

ZHANG Yuan-qin, XU Lu, MA Yi-ran, et al

Department of Blood Transfusion the First Affiliated Hospital of China Medical University, Shenyang 110000

Received:2022-05-12 Online:2022-10-20 Published:2022-10-31

Abstract

Abstract: Objective To discuss the auxiliary diagnostic value of and clinical applicability of Capillary centrifugation in high-risk pregnant women with massive fetomaternal hemorrhage（FMH）caused by maternal-fetal blood type inconsistency. Methods Twenty-five pregnant women in the second- and third-trimester pregnancy suspected of massive FMH caused by maternal-fetal blood type inconsistency were enrolled. The results of flow cytometry were used as the gold standard to evaluate the diagnostic performance of capillary centrifugation. Results In the 25 pregnant women, 15 cases were confirmed by flow cytometry to have undergone massive FMH, and 11 of them were successfully separated by Capillary centrifugation. The sensitivity, specificity, positive predictive value and coincidence rate of Capillary centrifugation for the diagnosis of massive FMH were 73.3%, 60%, 73.3% and 68%, respectively. Conclusion Capillary centrifugation has auxiliary experimental diagnostic value for massive FMH with maternal-fetal blood group incompatibility because it is simple and easy to operate.

Key words: Fetomaternal hemorrhage syndrome, Capillary centrifugation, Diagnostic value

CLC Number:

R457.1R714.5

ZHANG Yuan-qin, XU Lu, MA Yi-ran, et al. Massive Fetomaternal Hemorrhage Caused by Maternal-fetal Blood Type Inconsistency:Diagnostic Value of Capillary Centrifugation[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2022, 24(5): 582-587.

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Massive Fetomaternal Hemorrhage Caused by Maternal-fetal Blood Type Inconsistency:Diagnostic Value of Capillary Centrifugation

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