Abstract: Objective To explore the effect of platelet rich plasma (PRP) on traumatic synovitis of ankle joint. Methods From January 2021 to June 2022, 45 patients with traumatic synovitis of the ankle joint who were treated in the department of orthopedics and traumatology of a tertiary hospital were included. The patients were randomly divided into the observation group (20 cases, PRP treatment) and the control group (25 cases, traditional corticosteroid treatment) according to the random number table method. The ankle joint scores and clinical effects were compared between the two groups at before, 1, 3 and 6 months after treatment. Results The Baird-Jackson score and AOFAS score were higher (P<0.05) and VAS score was lower than before treatment in both groups after 1 month of treatment (P<0.05), and the control group was better than observation group (P<0.05). After 3 months of treatment, Baird-Jackson score and AOFAS score decreased (P<0.05) and VAS score increased (P<0.05) in the control group compared with one month after treatment. Baird-Jackson score and AOFAS score increased (P<0.05) and VAS score decreased (P<0.05) in the observation group compared with one month after treatment ( P<0.05), which was better than the control group (P<0.05). Time to first improvement in the control group was more common in 24 hours after treatment, and which was more common in 2 weeks and 1 month after treatment in the observation group (P<0.05). The total effective rate of the observation group was 95%, higher than that in the control group of 68% (P<0.05). Conclusion Traditional hormone therapy is fast-acting but short-sustained and prone to recurrence. PRP has better long-term effects and can improve patients' clinical symptoms for up to 6 months, which is worthy of clinical application.

Key words: Platelet Rich Plasma, Ankle joint, Traumatic synovitis, Corticosteroid