Abstract: Objective To analyze the recruitment strategy for and population characteristics of COVID-19 convalescent plasma (CCP) donors. Methods The questionnaire survey was conducted until March 1, 2021. Six contents including the recruitment of CCP donors, medical ethics compliance, standard for cured COVID-19 Patients, standard for pre-donation health consultation, and CCP donor demographics, were carried out. Results The three recruitment strategies of CCP donors from designated COVID-19 hospitals, blood center and both the two institutions accounted for 75.55%. Blood centers that collected disease course information and other general medical history accounted for 70%. Both the recruitment institutions and plasma collection institutions that were responsible for informed consent notification accounted for 68.3%. Collection institutions whose recruitment criteria met two consecutive negative COVID-19 nucleic acid test results, normal body temperature, self-isolate at home at least 14 days and normal medical imaging accounted for 41.60%. A total of 75.60% institutions have formulated health examination requirements or added additional requirements for CCP donors. Among the CCP donors, male donors accounted for 56.31%, and successful donations accounted for 74.90%. Conclusion The successful recruitment rate of CCP donors is low. It is better to recruit from designated hospitals and blood collection and supply institutions simultaneously. Informed consent and long rehabilitation time is the basis for ensuring the safety of CCP donations. Among the rehabilitated patients, men are more willing to donate CCP than women.

Key words: COVID-19, Convalescent plasma, Questionnaire, Plasma collection