Abstract: Objective To explore the clinical significance of thrombelastogragh（TEG） in children immune thrombocytopenia （ITP）. Methods The levels of blood TEG in 146 patients with ITP from the Beijing children's hospital were analyzed,and the Results were analyzed statistically. The cases were divided into three groups including therapy group,observation group and alleviate group according to the PLT levels. Results There were statistical differences among the three groups of R、K、Angle and MA（P<0.01）,while the treatment group was obviously lower than the reference value in MA and Angle,and difference exists in any two group in MA and Angle（P<0.01）. Although there was no difference between therapy group and observation group in R（P>0.05） and K（P>0.017）,there were differences between alleviate group and the others group in R（P<0.01） and K（P<0.017）. Conclusions TEG is important for the treatment of children immune thrombocytopenia。

Key words: Thrombelastograph, Immune thrombocytopenia, Platelet function