Abstract: Objective Analysis of effect of intraoperative autologous transfusion on coagulation function in patients with scoliosis. Methods According to transfusion volume accounted for the proportion of circulating blood volume,198 cases scoliosis with autologous blood transfusion technology were divided into 3 groups：group A transfusion volume is less than 10% of the circulating blood volume,group B transfusion volume of circulating blood volume accounted for 10%-50%,group C transfusion volume greater than the circulating blood volume 50%,hemoglobin （Hb）,hematocrit （HCT）,platelet （PLT）,prothrombin time （PT）,partial thromboplastin time （APTT）,fibrin original （FIB） were detected before and after transfusion. Results In group A Hb and HCT were increased after reinfusionthan （P<0.05）,but PLT and coagulation function without significant difference（P>0.05）.In group B,compared to before reinfusion,Hb and HCT were increased（P<0.05）,PT,APTT were prolonged,FIB was decreased after reinfusion（P<0.05）.In group C,transfusion after reinfusion,PLT and coagulation function significantly were decreased,（P< 0.05）,while Hb,HCT significantly improved （P<0.05）.Conclusion Autologous blood transfusion in children's scoliosis surgery is beneficial to reduce blood loss and allogeneic blood transfusion. For a large amount of blood loss,it is required for intraoperative monitoring of coagulation function,timely replenishment of fresh plasma,platelets or other coagulation factors.

Key words: Children Correction of scoliosis, Autologous blood transfusion, Coagulation function