Abstract: Objective To investigate the effect of restrictive and non restrictive blood transfusion in the treatment of low birth weight infants. Methods 79 cases medical records of low birth weight neonatal anemia during December 2013 Septembe 2015 year r in our hospital were retropectively analysed,according to the severity of anemia and hematocrit （Hct）value,divided into restrictive transfusion group （42 cases）and non restrictive transfusion group （37 cases）. All of first neonatal transfusion Hct,the first day age,blood transfusion per case,total volume of blood transfusion,blood transfusion each time,transfusion times were recorded,and two groups of treatment and complications were compared in neonates. Results Compared with the limited blood transfusion group,non restrictive transfusion group showed that Hct before blood transfusion first times was higher,however,blood transfusion before each age,total blood transfusion,blood transfusion number,low oxygen time,noninvasive mechanical ventilation time,CPAP time were lower（P<0.05）,The incidence of intracranial hemorrhage and nosocomial infection （28.57%,35.71%）in the restrictive transfusion group was higher than that in the non restrictive transfusion group （8.10%,13.51%）,（P<0.05）. There was no significant difference betweentwo groups in CPAP,oxygen,noninvasive mechanical ventilation,the number and time of aminophylline,and hospitalization time,in apnea,cerebral white matter damage,and then open the incidence of arterial catheter,（P>0.05）. Conclusion Non restrictive transfusion strategies,which can rectify the low birth weight neonatal anemia,shorten the time of mechanical ventilation and oxygen time,reduce the hospital infection and intracranial hemorrhage and other complications,is conducive to the improvement and rehabilitation.

Key words: Limited blood transfusion, Non restrictive blood transfusion, Low birth weight, Neonatal anemia