• 中国科学论文统计源期刊
  • 中国科技核心期刊
  • 美国化学文摘(CA)来源期刊
  • 日本科学技术振兴机构数据库(JST)

JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2016, Vol. 18 ›› Issue (3): 251-254.DOI: 10.3969/j.issn.1671-2587.2016.03.017

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Analysis of Biochemical Markers Associated with Clopidogrel Resistance after Percutaneous Coronary Interventions

LI guang-hua, YE lian-zhen, WANG jing-jian, et al   

  1. Guangdong General Hospital/ Guangdong Academy of Medical Science, Guangzhou 510080
  • Received:2015-09-26 Online:2016-06-20 Published:2016-09-21

Abstract: ObjectiveTo observe the incidence and the influential factors of clopidogrel resistance (CPGR) in patients who received percutaneous coronary interventions(PCI). MethodsEighty six patients with PCI were subjected to the study. Light transmittance aggregometry was used to measure platelet aggregation (PA) induced by adenosine diphosphate (ADP) before and 5-7 days after clopidogrel intake. The △P measurements were based on the standard of △P ≤ 10% CPGR (negative values included) . The patients were divided into CPGR group and none CPGR group according to the △P. The relation between CPGR and the patients’ relevant clinical biochemical indexes was observed. Results

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