1 中华医学会内分泌学会,中华医学会围产医学会.妊娠及产后甲状腺疾病诊治指南[J].中华围产医学杂志,2012,15(2):385-483. 2 Li Z,Tan F,Thiele CJ. Inactivation of glycogen synthase kinase-3beta contributes to brain derived neutrophic factor/TrkB- induced resistance to chemotherapy in neuroblastoma cells[J]. Mol Cancer Ther,2007,6(12):3113-3121. 3 Surks MI,Ortiz E,Daniels GH,et al. Subclinical thyroid disease:scientifi review and guidelines for diagnosis and management[J].JAMA,2011,291(2):228-238 4 Casey BM,Dashe JS,Wells CE,et al.Subclinical hypothyroidism and pregnancy outcomes[J].Obstel Gynecol,2005,105(2):239-245. 5 Casey BM. Subclinical hypothyroidism and pregnancy[J]. Obstetrical& gynecological survey,2006,61(6):415-420. 6 Abalovich M,Amino N,Barbour LA,et al. Management of thyroid dysfunction during pregnancy and Postpartum:an Endocrine Society clinical Practice Guideline[J].J Clin Endocrinol Metab,2011,92(8):S1-S47. 7 Sahu MT,Das V,Mittal S,et al. Overt and subclinical thyroiddysfunction among Indian pregnant women and its effect on maternaland fetal outcome[J]. Arch Gynecol Obstet,2010,281(2):215. 8 Cleary-Goldman J,Malone FD,Lambert-MesserlianG,etal.Maternal thyroid hypofunction and pregnancy outcome[J].ObstetGynecol,2008,112(1):85-92. 9 刘娜,边旭明,高劲松,等. 妊娠合并甲状腺功能减退症或亚临床甲状腺功能减退症 77 例临床分析[J].中华围产医学杂志 ,2009,12(3):186-189. 10 Abalovich M,Amion N,Barbour LA,et al. Management of thyroiddysfunction during pregnancy and postpartum :an endocrine society clinical practice guideline[J]. J Clin Endocrinol Metabolism,2011,92(8):S1-S27. 11 Negro R,Schwartz A,Gismondi R,et al.Universal screening versus case finding for detection and treatment of thyroid hormonal dysfunction during pregnancy[J]. I Clin Endocrinol Metab,2010,95(4):1699-1707. 12 Seoane Cruz I,Pen ín alvarez M,Luna Cano R,et al. Treatment with fixed thyroxine doses in pregnant women with subclinical hypothyroidism [J]. Endocrinol Nutr,2012,59(5):284-287.