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JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2022, Vol. 24 ›› Issue (6): 687-692.DOI: 10.3969/j.issn.1671-2587.2022.06.002

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Application Prospect of Cell Therapy in Kidney Transplantation

LI Yang, RONG Rui-ming   

  1. Blood Transfusion Department of Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032
  • Received:2022-09-15 Published:2023-01-05

Abstract: Organ transplantation can be carried out to prolong their lives when patients get end-stage organ failure. However, organ structure and function damage and immune rejection after transplantation impair patients' survival time and quality. Cell therapy has been widely accepted as an effective way in regenerative medicine and it is mainly divided into stem cell therapy and immune cell therapy. Cell therapy has achieved significant therapeutic effect in organ transplantation. Taking kidney transplantation as an example, this paper will discuss how to regulate the immune balance of organ transplantation and prolong the vitality of transplanted organs and patients by cell therapy. These will provide new insights for the induction and maintenance of organ transplantation tolerance.

Key words: Cell therapy, Kidney transplantation, Immune cells

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