Transfusion Medicine 3.0: Intelligence and Personalization in Transfusion Medicine

doi:10.3969/j.issn.1671-2587.2025.06.002

JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2025, Vol. 27 ›› Issue (6): 754-760.DOI: 10.3969/j.issn.1671-2587.2025.06.002

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Transfusion Medicine 3.0: Intelligence and Personalization in Transfusion Medicine

GE Shuang, SHANG Wei, YU Yang, WANG Deqing

Department of Transfusion Medicine, The First Medical Center of Chinese PLA General Hospital, Beijing 100039

Received:2025-06-19 Published:2025-12-24

Abstract

Abstract: Transfusion medicine is undergoing a significant transformation from traditional empirical medicine to modern precision medicine. This article systematically reviews the development of transfusion medicine from two dimensions: hardware (blood component research) and software (management system). The evolution encompasses three stages: the 1.0 cognitive initiation phase characterized by blood typing and whole blood transfusion, the 2.0 development phase marked by blood component preparation and standardized management, and the current 3.0 innovation phase featuring intelligence and personalization. In the 3.0 era, gene editing technology has facilitated the development of universal blood, the directed differentiation of stem cells has enabled the in vitro culture of blood cells, and the introduction of artificial intelligence has optimized transfusion decision-making and blood management. These technological innovations are driving transfusion medicine into a new era of precision medicine. This article provides an in-depth analysis of emerging technologies' applications in transfusion medicine and explores the opportunities and challenges brought by multidisciplinary integration, offering new perspectives for the future development of transfusion medicine.

Key words: Transfusion Medicine, Precision medicine, Intelligence, Personalization

CLC Number:

R457

GE Shuang, SHANG Wei, YU Yang, WANG Deqing. Transfusion Medicine 3.0: Intelligence and Personalization in Transfusion Medicine[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2025, 27(6): 754-760.

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