Abstract: ObjectiveTo evaluate the quality of pooled platelet and leukocyte depletion,for supplying quality assurance for clinical transfusion. MethodsPlatelet concentrates (PCs) was prepared from 400 ml fresh whole blood by platelet rich plasma ( PRP) method. 12 units of ABO-matched PCs were pooled. and filtered with the domestic filters. The indicators of PCs were tested before and after filtration. ResultsThe number of platelet(Plt), red blood cell(RBC), leukocyte(WBC), pH and hypotonic shock response( HSR) before and after filtration were（3.20±0.37）x 1011 VS（2.67±0.44）x 1011,（4.39±1.97）x 109 VS（3.95±1.77）x 109,（2.06±2.02）x 108 VS（0.02±0.03）x 108, 6.78±1.18 VS 6.98±1.06,（68.53±9.18）% VS（70.96±7.81）%. The platelet recovery was（82.67±5.58）%. There were significant difference(P < 0. 05) among these indicators, such as PH,RBC and WBC. ConclusionPooling and filtering platelet concentrate is worthy of clinical use due to its standard quality and well-preserved function after filtration.

Key words: Platelet, concentrate, Pool, Filtering, out, eukodepletion, Quality, indicators