• 中国科学论文统计源期刊
  • 中国科技核心期刊
  • 美国化学文摘(CA)来源期刊
  • 日本科学技术振兴机构数据库(JST)

JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2020, Vol. 22 ›› Issue (2): 113-117.DOI: 10.3969/j.issn.1671-2587.2020.02.001

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Clinical Significance of Platelet Antibody Detection——Based on Study of 2 338 Case from10 Institutions in China

HUANG Xue-yuan, CHEN Bing-yu, ZHOU Ming, et al   

  1. The Third Xiangya Hospital of Central South University 410013
  • Received:2019-10-30 Online:2020-04-20 Published:2020-04-16

Abstract: Objective To explore the relationship between platelet antibodies and disease symptom, weinvestigatedthe clinical datafromthe detectionof plateletantibodies in 10 institutions of China. Methods The demographic, clinical and laboratory data of patients who were detectedin platelet antibodies in 10 institutions across the country from July 1, 2018 to June 30, 2019 were collected and statistically analyzed for platelet transfusion refractory. Relationship between Fetal and neonatal alloimmune thrombocytopenia (FNAIT), abortion and stillbirth, and immune thrombocytopenia. Results Among the 2 338 patients, the positive rate of platelet antibody in patients with platelet transfusion refractory, FNAIT patients, abortion and stillbirth patients, and immune thrombocytopenia was higher than that in patients without the above disease (control group). Conclusion Platelet antibody detection is important in the prevention and diagnosis of platelet transfusion refractory, FNAIT, abortion and stillbirth, and immune thrombocytopenia. It should be included in the routine laboratory examination of the above diseases.

Key words: Platelet antibodies detection, Platelet transfusion refractory, FNAIT, Abortion, Stillbirth, Immune thrombocytopenia

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