关键词: 自体血小板分离回输, 主动脉夹层, 血液保护, 短期预后

Abstract: Objective To compare the efficiency of autologous plateletpheresis (APP) transfusion and allogeneic apheresis platelet transfusion on the blood protection and the short-term outcome of type A aortic dissection (TAAD). Methods A retrospective review was performed of 78 patients who underwent TAAD operation in our hospital between June 2019 and December 2021. Of which 40 patients received APP transfusion and 38 patients in the control group received 1U of allogeneic apheresis platelet transfusion. The preoperative waiting time, intraoperative blood loss, output from postoperative chest tube, perioperative blood transfusion, ventilation time, length of stay (LOS) in the intensive care unit (ICU), hospital stay, and the incidence of perioperative complications and in-hospital mortality between the two groups were analyzed. Results The preoperative waiting time in APP group was significantly shorter than that in the control group (Z=-2.48,P< 0.05). The ventilation time was shorter, too. (Z =-2.20, P<0.05). Postoperative pulmonary infection rate was 17.5%, significantly lower than that in the control group (χ²=4.65, P<0.05). The intraoperative and perioperative transfusion of red blood, plasma and cryoprecipitate were significantly lower than those in the control group (P<0.05). There were no significant differences between the two groups in intraoperative blood loss, ICU LOS, hospital stay and in-hospital mortality. Conclusion Compared with allogeneic platelet transfusion, APP transfusion can effectively reduce the preoperative waiting time, mechanical ventilation time, postoperative pulmonary infection rate and perioperative allogeneic blood transfusion use, so as to better blood protection effect, but it has no significant improvement on the short-term outcome of patients.

Key words: APP, TAAD, Blood protection, Outcome