• 中国科学论文统计源期刊
  • 中国科技核心期刊
  • 美国化学文摘(CA)来源期刊
  • 日本科学技术振兴机构数据库(JST)

临床输血与检验 ›› 2025, Vol. 27 ›› Issue (3): 289-290.DOI: 10.3969/j.issn.1671-2587.2025.03.001

• 专家述评 •    下一篇

RhCE抗原错配是中国输血患者的主要风险

赵桐茂   

  1. 原美国国立卫生研究院, 马里兰州 贝塞斯达 20892
  • 收稿日期:2025-04-10 发布日期:2025-06-23
  • 作者简介:赵桐茂,主要从事免疫血液学和免疫遗传学研究,(E-mail)tomzhao407@hotmail.com。
  • 基金资助:
    *本课题受陕西省科技厅科技成果转移与推广计划-获奖成果转化项目(No.2019CGHJ-09),陕西省人民医院领军人才基金项目(No.2021LJ-14)资助

RhCE Antigen Mismatch is the Main Risk for Chinese Transfusion Patients

ZHAO Tongmao   

  1. National Institutes of Health, Bethesda 20892 USA
  • Received:2025-04-10 Published:2025-06-23

摘要: 中国人红细胞意外抗体和Rh血型分布大数据显示,在住院患者的意外抗体中,抗-RhCE抗体占比(41.94%)是抗-RhD抗体占比(8.93%)的4.7倍;在随机输血中,RhCE抗原错配概率(25.16%)是RhD抗原错配概率(0.49%)的51.4倍。这些数据表明RhCE抗原错配是中国输血患者的主要风险,制定适合中国患者的RhCE抗原匹配输血策略对于输血安全至关重要。

关键词: 红细胞意外抗体, Rh血型, Rh同种抗体, RhCE抗原匹配, 精准输血, 输血安全

Abstract: The big data of unexpected red blood cell antibody and Rh blood group distribution in Chinese population shows that the proportion of anti-RhCE antibody (41.94%) is 4.7 times higher than that of anti-RhD antibody (8.93%) among unexpected antibodies in hospitalized patients. In random blood transfusion, the probability of RhCE antigen mismatch (25.16%) is 51.4 times higher than that of RhD antigen mismatch (0.49%). These data indicate that RhCE antigen mismatch is the main risk for Chinese transfusion patients, and establishing RhCE antigen matching transfusion strategies suitable for Chinese patients is crucial for transfusion safety.

Key words: Unexpected red blood cell antibody, Rh blood group, Rh alloantibody, RhCE antigen matching, Precise transfusion, Transfusison safety

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