• 中国科学论文统计源期刊
  • 中国科技核心期刊
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  • 日本科学技术振兴机构数据库(JST)
临床输血与检验

临床输血与检验 ›› 2017, Vol. 19 ›› Issue (3): 227-230.DOI: 10.3969/j.issn.1671-2587.2017.03.005

• 临床输血 • 上一篇    下一篇

臭氧灌注联合自体血回输对激素性股骨头坏死患者脂质代谢紊乱的影响*

刘亚妹, 柴俊龙, 郑继会, 胡思斌   

  1. 061000 河北省沧州中西医结合医院麻醉科（刘亚妹）; 疼痛科（柴俊龙）; 骨科（郑继会,胡思斌）
  • 收稿日期:2016-12-28 出版日期:2017-06-20 发布日期:2017-06-23
  • 作者简介:刘亚妹（1978-）,女,河北沧州人,主治医师,学士,主要从事临床麻醉学工作,（E-mail）tobabu31@163.com。
  • 基金资助:
    *本课题受沧州市科学技术研究项目（No.14302144）资助

The Effect of Ozone Infusion Combined with Autotransfusion on Lipid Metabolism Disorders in Patients with Steroid-induced Necrosis of Femoral Head

LIU Ya-mei, CHAI Jun-long, ZHENG Ji-hui, et al   

  1. Department of Anesthesia,Hospital of Traditional Chinese and Western Medicine,Cangzhou,Hebei 061000
  • Received:2016-12-28 Online:2017-06-20 Published:2017-06-23

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摘要： 目的 观察臭氧灌注联合臭氧自体血回输对激素性股骨头坏死患者脂质代谢紊乱的影响。方法 选取本院2014年9月~2015年12月治疗的Ficat分期Ⅰ、Ⅱ期的120例激素性股骨头坏死合并脂质代谢紊乱患者,按照数字表法随机分为3组,每组各40例。观察组给予关节腔注射消炎镇痛液、臭氧灌注联合臭氧自体血回输,第1对照组给予关节腔注射消炎镇痛液及臭氧灌注,第2对照组给予关节腔注射消炎镇痛液及臭氧自体血回输,2个月后对比3组患者血脂水平及临床疗效。结果 治疗后观察组总有效率为90.00%,明显高于其余两组,与第1对照组比较差异有统计学意义（χ2=4.02,P<0.05）,与第2对照组比较差异无统计学意义（χ2=0.95,P>0.05）;治疗后所有患者血脂水平均有所改善,但是观察组各指标明显低于其余两组,且组间比较差异有统计学意义（P<0.05）。结论 臭氧灌注联合臭氧自体血回输可有效改善激素性股骨头坏死患者血脂水平,且治疗效果满意,值得进一步推广。

关键词: 臭氧, 自体血回输, 股骨头坏死, 脂质代谢

Abstract: Objective To observe the effect of ozone perfusion combined with ozone autologous blood transfusion on lipid metabolism disorders （LMD） in patients with steroid induced necrosis of the femoral head（SINFH）. Methods One hundred and twenty patients with SINFH and LMD were selected and randomly divided into three groups,with 40 cases in each. The experimental group was given the joint cavity injection of anti-inflammatory analgesic liquid,ozone perfusion combined with ozone autologous blood transfusion; the first control group was given the joint cavity injection of anti-inflammatory and analgesic liquid and ozone perfusion; and the second control group was given the joint cavity injection of anti-inflammatory and analgesic solution and ozone autologous blood transfusion. After 2 months the blood lipid levels and clinical efficacy were compared in the three groups of patients. Results After treatments,the total effective rate of experimental group was 90%,significantly higher than the other two groups（χ2=4.02,P<0.05）. No significant difference was noted between the second control group and the experimental group（χ2=0.95,P>0.05）. The blood lipid level of all patients were decreased but the indexes in experimental group were significantly lower than the other two groups（P<0.05）. Conclusion Ozone perfusion combined with ozone autologous blood transfusion can effectively attenuate the blood lipid level in patients with steroid induced femoral head necrosis,and the therapeutic effect is satisfactory.

Key words: Ozone, Autologous blood, transfusion, Necrosis of femoral head, Lipid metabolism

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