Abstract: Objective To analyze the value of anti-Mullerian hormone （AMH） in sera and follicular fluids on the day of oocyte retrieval to predict the outcome of superovulation in vitro fertilization in those with polycystic ovary syndrome （PCOS）. MethodForty eight patients with IVF-ET were selected as group PCOS and 52 with oviduct infertility treated with IVF-ET as the control. The general condition,AMH in sera and the follicle fluids of the pregnant and non-pregnant patients,and clinical features of the IVF-ET treatment cycle were compared.Results The levels of AMH in the sera and follicle fluids of group PCOS were （7.4±4.1） ng/mL and （3.9±2.1） ng/mL,respectively,which was higher than those of the control [（3.5±1.9） ng/mL and （1.7±1.1） ng/mL （t=6.180,P<0.05; t=5.500,P<0.05]. A total of 998 ovarian follicles and 570 eggs were obtained in group POCS,while 687 follicles and 476 eggs were obtained in the control. There was no significant difference in the rates of normal fertilization,high quality embryo,clinical pregnancy,early abortion as well as continuing pregnancy between the two groups [64.1% vs 69.4%,（39.3±26.5）% vs （38.8±23.4）%,45.8% vs 46.2%,18.2% vs 12.5%,and 37.5% vs 40.4%,P>0.05]. However,the rates of obtained eggs and egg maturation varied （57.1% vs 69.3%,77.9% vs 88.2%,P<0.05）. The difference existed in the AMH levels of follicle fluids and sera between pregnant and non-pregnant patients in POCS patients [（10.7±4.1）% vs （4.5±1.7）%,（5.2±2.0）% vs （3.0±1.5）%,P<0.05]. A significant difference was seen in the ratio of high quality embryos,AMH of follicular fluids and sera between pregnancy and non-pregnancy patients in the control group （50.7±18.4）% vs （27.2±21.2）%,（4.7±2.1）% vs （2.2±1.1）%,（1.9±1.0）% vs （1.2±0.6）%,and P<0.05].Conclusion The AMH value in follicular fluids and sera may reflect the clinical features of PCOS during IVF-ET process and help to predict the superovulation outcomes of IVF cycle in PCOS patients but not the outcomes of pregnancy after IVF-ET.

Key words: Anti-Mullerian hormone, Assisted reproductive technique, Polycystic ovary syndrome