Abstract: Objective To compare the consistency of the results of hypersensitive c-reactive protein （hs-CRP） detected by three different instruments. Methods From march to July, 2018, 156 cases of patients with infection and fever who visited the outpatient department of Longhua district people's hospital in Shenzhen were selected. Using AU5800 as the reference instrument and VITROS5600 and 5390 as the comparison instruments, the consistency of hs-CRP test results of three different instruments was analyzed. Results In serum of 156 cases of hs-CRP reference instrument test results concentration was 93.64±79.74 mg/L, Mindray 5390 automatic blood corpuscle-hypersensitive c-reactive protein all-in-one test results was 87.98±76.57 mg/L, there was no statistically significant difference between the two （t=0.912 4, P>0.05）, while VITROS5600 dry piece of biochemical analyzer test results was 182.38±158.79 mg/L, significantly higher than the reference instrument, the difference was statistically significant （t=6.805 6, P<0.05）. The correlation coefficient （r） between hs-CRP concentration detected by the three instruments was 0.968 5. The correlation coefficient （r） between VITROS5600 and AU5800 was 0.953 0. Conclusion The results of hs-CRP detected by 5390 hemocyte-hypersensitive c-reactive protein integrator and AU5800 biochemical analyzer were consistent, while the results detected by VITROS5600 dry platebiochemical immune analyzer were obviously higher, but the hs-CRP detected by 3 different instruments showed good positive correlation.

Key words: Johnson & Johnson VITROS5600, Beckman AU5800, Mindray BC-5390, Hypersensitive c-reactive protein, Consistency