Abstract: Objective To establish a SARS-CoV-2 related detection platform suitable for pretransfusion laboratories to avoid biological risks. Methods An automated SARS-CoV-2 detection platform was established by modifying the automatic sampler program, adjusting the liquid curve, reducing the injection speed, performing sub-surface addition and mixing, editing the enzyme immunoassay and LIS program and optimizing the nucleic acid pooling program. Results The IgM and IgG antibody,IgG antibody with its titre,and nucleic acid of coronavirus in plasma from cured COVID-19 patients were successfully detected on the platform. Conclusion The established platform could realize automated and standardized sample addition and detection, and avoid biosafety risks. It may provide a favorable strategy for the recovery period plasma detection which could be helpful in COVID-19 treatment.

Key words: Novel coronavirus, Automation, Enzyme immunoassay, Nucleic acid detection