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JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2021, Vol. 23 ›› Issue (3): 314-318.DOI: 10.3969/j.issn.1671-2587.2021.03.006

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Analysis of the Application of Autotransfusion in the Operation of Gynecological Tumor Patients

QIN Yu-si, LI Yuan-bo, XUE Ying-hong, et al   

  1. Department of Blood Transfusion, Guangxi Medical University Cancer Hospital, Nanning, Guangxi 530021
  • Received:2021-01-28 Online:2021-06-20 Published:2021-06-22

Abstract: Objective To explore the application and effect of autotransfusion in patients with gynecological tumor surgery. Methods A retrospective analysis of blood transfusion in 432 gynecological tumor patients undergoing surgery was conducted. Patients with cervical cancer and ovarian tumor were selected and divided into observation group (autologous blood transfusion) and control group (allogeneic blood transfusion). The changes of immunological and hematological indexes were compared between the two groups. Results ①Among the 432 patients diagnosed after operation, cervical cancer accounted for 40%, ovarian tumors accounted for 30%, other gynecological tumors accounted for 30%, and the blood consumption was 1 325.5 U. In 199 cases, 295 U of autologous blood was collected preoperatively, and the rate of autologous blood transfusion was 22.26%. ②In the aspect of immunity, IgG in observation group was significantly decreased after operation in patients with cervical cancer (P<0.05). Comparison between groups, CD4+/CD8+ ratio of T lymphocytesdecreased significantly in control group (P<0.05). In hematology, TT was significantly prolonged in the observation group (P<0.05). ③In ovarian tumor patients, IgM, IgG and IgA in observation group were significantly decreased (P<0.05). Conclusion There was no significant difference in the effect of the two transfusion methods on the immunological and hematological function of gynecological tumor patients in the short term. The indexes of patients with autologous blood transfusion would not be abnormal due to the decrease of circulating blood volume after blood collection.

Key words: Malignant tumor, Autotransfusion, Allogenetic transfusion, Elective surgery, Effect of blood transfusion

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