Abstract: Objective To compare the effects of autotransfusion of pre-stored blood and allogeneic transfusion on the immune function and postoperative recovery of patients undergoing non-stop coronary artery bypass grafting. Methods Eighty-five patients who underwent non-stop coronary artery bypass grafting from February 2017 to February 2019 in our hospital were selected for the study. Among them, 48 patients with allogeneic blood transfusion were set as group A, and 37 patients who voluntarily received autotransfusion of pre-stored blood were set as group B the blood routine, coagulation function, cellular immune function, auxiliary ventilation time and ICU stay time before and after operation were compared between the two groups. Results 1 The RBC, Hb, PLT and HCT of the two groups decreased at 24 hours after operation (P<0.05), WBC of group B was lower than that of group A, RBC, Hb and PLT were higher than that of group A at 24 hours after operation (P<0.05); 2 Compared with before operation, the percentage of CD3⁺cells and CD8⁺cells in group A decreased and the percentage of CD4⁺cells increased at 24 hours after operation (P<0.05), the difference was statistically significant (P<0.05) .At 24 hours after operation, the percentage of CD3⁺cells and CD4⁺/CD8⁺ in group B was higher than that in group A, and the percentage of CD8⁺cells was lower than that in group A (P<0.05); 3 The time of auxiliary ventilation and ICU stay in group B were less than that in group A (P<0.05). Conclusion Autotransfusion of pre-stored blood can effectively improve the cellular immune function, balance the relationship between oxygen supply and demand, and reduce the time of auxiliary ventilation.

Key words: Autotransfusion, of, pre-stored, blood, Allogeneic, transfusion, Off-pump, coronary, artery, bypass, grafting, Coagulation, function, Immune, function