Abstract: Objective To discuss risk factors for adverse reactions and strategies for nursing during perioperative autologous blood donation. Methods A total of 2 036 patients with pre-operative autologous blood donation (PABD) in the first medical center of Chinese PLA General Hospital between January 2017 and May 2019 were selected. We collected general data of patients before donation, recorded the incidence, types and factors associated with adverse events (AEs) during PABD procedure, and worked out strategies for nursing. Results Among the 2 036 patients included in the study, 31 (1.52%) experienced adverse reactions, of which vertigo (64.52%), weakness and sweating (41.94%), pallor (38.71%), nausea (25.81%) were the most common. Age, with underlying medical conditions, stressful blood draw and the number of punctures were the main risk factors associated with AEs during PABD. Conclusion In view of risk factors associated with adverse reactions, the corresponding PABD management and strategies for nursing can effectively reduce the incidence of adverse reactions to protect patients to the greatest extent, and ultimately, ensure the operation smoothly.

Key words: Autologous blood collection, Adverse reactions, Risk factors, Nursing strategies