Research Progress on the Effect of Cryopreservation on Platelets Structure and Function

doi:10.3969/j.issn.1671-2587.2025.05.017

JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2025, Vol. 27 ›› Issue (5): 695-700.DOI: 10.3969/j.issn.1671-2587.2025.05.017

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Research Progress on the Effect of Cryopreservation on Platelets Structure and Function

LI Jiao, LI Jianping, LI Xiaofeng

Liaoning Provincial Blood Center Liaoning Transfusion Medicine Institute, Shenyang 110044

Received:2025-09-02 Revised:2025-09-11 Online:2025-10-20 Published:2025-10-11

Abstract

Abstract: The maintenance of platelet function and viability directly impacts clinical outcomes, yet the effects of cryopreservation on platelets remain a critical area requiring further investigation. With over 70 years of research history, cryopreservation protocols—including selection of freezing methods, cryoprotectants, and storage duration—significantly influence platelet characteristics and functional parameters. While cryopreservation technology enables long-term storage, clinical applications still face challenges such as restoring thawed platelet function and ensuring effective transfusion outcomes. This review synthesizes recent advancements to provide theoretical foundations and practical guidance for optimizing platelet cryopreservation techniques, ultimately enhancing clinical efficacy in platelet utilization.

Key words: Platelet, Cryopreservation, Function

CLC Number:

R457

LI Jiao, LI Jianping, LI Xiaofeng. Research Progress on the Effect of Cryopreservation on Platelets Structure and Function[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2025, 27(5): 695-700.

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Research Progress on the Effect of Cryopreservation on Platelets Structure and Function

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