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JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2025, Vol. 27 ›› Issue (3): 408-411.DOI: 10.3969/j.issn.1671-2587.2025.03.020

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A Case Report on Allogeneic Platelet-rich Plasmag for Dorsal Hand Tendon Exposure Caused by Mannitol Extravasation

PENG Qing1, QI Qing2, HUANG Xiuling1, GU Yu1, XUE Jiayu1, YU Jing1, JING Yilin1, CHEN Lin1, LUAN Jianfeng2, WANG Shujun2   

  1. 1Wound care Center of Outpatient Department, General hospital of eastern theater command, PLA;
    2Department of Blood Transfusion, General hospital of eastern theater command, the affiliated hospital of Medical School of Nanjing University, Nanjing 210002
  • Received:2024-12-13 Published:2025-06-23

Abstract: Objective To summarize the treatment experience of allogeneic platelet-rich plasma in patients with exposed opisthenar tendons caused by mannitol extravasation. Methods According to the patient's wound condition, the staged treatment protocol was formulated in patients. RuyiJinhuangsan was applied externally to reduce inflammation and relieve pain in the inflammatory response stage, nano silverion dressing was used to wound packing with the infection control stage to promote exudate drainage and strengthen local infection control, red light therapy can improve local blood circulation, accelerating the absorption of inflammatory substances and reducing pain, and allogeneic platelet-rich plasma (PRP) treatment was performed to promote wound healing in the wound tendon exposure stage. Results From October 21, 2022 to November 11, 2022, after three PRP applications, and the patient's wound healing time was greatly shortened. Conclusion Allogeneic PRP demonstrated therapeutic efficacy in accelerating wound healing for dorsal hand tendon exposure secondary to mannitol extravasation.

Key words: Mannitol, Tendon exposure, Platelet rich plasma

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