Abstract: This study explores the application and potential impact of Digital Twin technology in transfusion medicine. Through a systematic review of relevant literature, we first outline the fundamental concepts and evolution of Digital Twin technology. We then conduct an in-depth analysis of its extinct advantages in optimizing blood collection and supply processes, enhancing transfusion procedures, and improving transfusion safety. Special emphasis is placed on its role in data governance and intelligent management within blood services. Additionallly, we examine the challenges related to data security, privacy protection, regulatory compliance, and medical ethics that arise with the implemention of this technology. Our findings indicate that while Digital Twin technology holds significant promise for transfusion medicine, several practical issues remain to be addressed. Future efforts should aim to effectively harness Digital Twin frameworks to foster innovation, ultimately providing evidence-based operational solutions and technical guidance for blood services while advancing transfusion safety.

Key words: Digital twin, Transfusion medicine, Data security, Medical ethics