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JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2026, Vol. 28 ›› Issue (3): 445-450.DOI: 10.3969/j.issn.1671-2587.2026.03.023

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Research Advances in Eosinophils in Tissue Injury Repair

CHEN Haonan1,2, YAN Ying3, LI Ming2   

  1. 1School of Laboratory Medicine, Bengbu Medical University, Bengbu 233030;
    2Department of Laboratory Medicine, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230031;
    3Department of Medical Oncology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230031
  • Received:2025-07-16 Published:2026-07-07

Abstract: Eosinophils are a subset of immune cells with low abundance in humans but play critical roles in immune regulation and inflammation, traditionally associated with allergic diseases and parasitic infections. Recent studies have increasingly clarified their mechanisms in mediating damage repair within distinct tissue microenvironments. The regulatory roles of eosinophils in tumor microenvironment and tissue damage repair have emerged as cutting-edge research areas. This review systematically summarizes the functional contributions of eosinophils in multiple tissue injuries and their underlying mechanisms, aiming to provide novel theoretical basis and insights for early screening, treatment, and prevention of related diseases.

Key words: Eosinophils, Tissue damage, Inflammation, Immune regulation

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