Abstract: Objective To systematically analyze and evaluate the blood donors' real experiences with voluntary blood donation, providing a theoretical basis for the subsequent activities. Methods A qualitative systematic review was conducted by searching Web of Science, PubMed, The Cochrane Library, EmBase, CINAHL, CNKI, CBM, Wanfang, and VIP databases from inception to April 1, 2026. Study quality was assessed using the Joanna Briggs Institute (JBI) critical appraisal checklist for qualitative research, followed by meta-analysis of the findings. Results A total of 25 articles were included, yielding 57 distinct findings categorized into 10 categories and synthesized into four integrated findings: (1) complex, intertwined physical and emotional experiences; (2) blood donation decisions influenced by multiple drivers and practical constraints; (3) interpersonal interactions and service experiences during blood donation services, and (4) the formation of sustained donation intention through perceived social support. Based on these findings, a standardized service improvement checklist incorporating specific items adapted for county- and township-level mobile blood collection. construct a standardized service improvement checklist was developed, incorporating specific items adapted for county- and township-level mobile blood collection. Conclusion Blood management authorities should enhance service quality while prioritizing emotional support and donor incentive preferences. Government departments should optimize incentive mechanisms and leverage online platforms for health education. Additionally, developing stratified nursing guidelines tailored for primary care settings will provide practical references, thereby stabilizing the donor base, boosting motivation, and promoting the high-quality, sustainable development of voluntary blood donation.

Key words: Voluntary blood donation, Psychological experience, Qualitative research, Meta-synthesis, Donation intention