Abstract: Objective We analyzed the postoperative blood transfusion in patients undergoing uterus transplantation (UTx),and discussed transfusion strategy and evaluated the efficacy. We formulated the transfusion plan to ensure the blood transfusion safety. Methods We retrospectively reviewed the clinical data of 2 cases of patients with UTx performed in January 2016 and January 2018. We analyzed hemoglobin,coagulation disorders and clinical blood use in postoperative period. We repeated compatibility testing. Red cells were transfused with blood type compatibility and non-red cells blood products were transfused with the same blood type. We observed changes in blood routine,coagulation,blood biochemistry and other indicators of patients before and after transplantation,and evaluated the effectiveness of transfusion. Results Perioperative changes in blood routine and coagulation functions in 2 patients with UTx were obviously caused by various factors. Leukoreduced and irradiated packed red blood cells were given after surgery for supportive treatment. Combined with multidisciplinary clinical treatment,patients recovered and were discharged from hospital. Conclusion The cause that hemoglobin drop acutely in uterine transplantation patient should be taken into account in many factors. While improving blood transfusion related serological examination,the clinical diagnosis and treatment process of patients should be comprehensively considered. Transfusion strategy and clinical treatment plan should be given to ensure patient safety.

Key words: Parental uterine transplantation, Combined transfusion, Therapeutic effect of blood transfusion, Blood transfusion safety