JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2019, Vol. 21 ›› Issue (2): 190-193.DOI: 10.3969/j.issn.1671-2587.2019.02.022
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HUANG Yan-ni, YUAN Yan-ping, XIAO Xue-mei
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Abstract: Objective To investigate the relationship between serum hypersensitive C-reactive protein (hs-CRP) and carotid artery stenosis and restenosis after carotid artery stenting (CAS),so as to provide references for its clinical application. Method sOne hundred and sixty-eight patients undergoing CAS were selected in the hospital. The level of serum hs-CRP of pre-operation and 1d,7d,3 mon and 6 mon post-operation was measured. The relationship was analyzed between serum hs-CRP level and the degree of stenosis and restenosis following CAS. Results The incidence of carotid stenosis increased with the level of serum hs-CRP (P<0.05) before operation. The incidence of restenosis was 19.05% (32/168) after 6 months of operation. No difference of the serum hs-CRP level was noted at pre-operation and 1d post-operation between the patients of restenosis and non-restenosis (P>0.05). The serum hs-CRP level in the patients of restenosis was significantly higher than that in those of non-restenosis on 7 d,3 mon and 6 mon post-operation,while the patients of non-restenosis had a higher level of △hs-CRP than those of restenosis (P<0.05). The serum hs-CRP level in all the patients increased significantly on day 1 after surgery,and it remained a high level after 7d of surgery in the patients of restenosis compared with those of pre-operation. However,the hs-CRP level was significantly decreased in the patients of no-restenosis (P<0.05). Multivariate regression analysis showed that △hs-CRP was an independent risk factor for restenosis after CAS. Conclusion The remarkable increase of serum hs-CRP was positively associated with the carotid stenosis following CAS,suggesting a predict marker for carotid artery restenosis.
Key words: Hypersensitive C-reactive protein, Carotid artery stenosis, Carotid artery stenting, Restenosis predictive value
CLC Number:
R446.11R743.3
HUANG Yan-ni, YUAN Yan-ping, XIAO Xue-mei. A Predictive Value of Serum Hypersensitive C-reactive Protein in Restenosis Following Carotid Artery Stenting[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2019, 21(2): 190-193.
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