Abstract: Objective To analyze the influencing factors of red blood cell transfusion in patients with hematopoietic stem cell transplantation so as to improve the efficacy of blood transfusion. Methods The fundamental information before and after transfusion in patients who had underwent hematopoietic stem cell transplantation were retrospectively analyzed from January 2016 to December 2016. The changes in hemoglobin were used as the dependent variables whereas other indicators, as independent variables. The model of multi-factor linear regression analysis was used to calculate the influencing factors of transfusion. Results A total of 409 person-times of transfusions were performed in 89 patients with hematopoietic stem cell transplantation. The heart rate, height, weight, volume of single transfusion, and days of blood preservation were considered as influencing factors. Conclusion Patients with hematopoietic stem cell transplantation benefit from the blood with fresh preservation. For patients in the blood group transition stage, individual strategy should include the blood according to specific serological patterns.

Key words: Hematopoietic stem cell transplantation, Red blood cell transfusion, Effect of blood transfusion, ABO blood group