Abstract: Objective To investigate the therapeutic effect and correlation analysis of peripheral lymphocyte and neutrophil ratio （LNR） and ratio of lymphocytes to monocytes in patients with nasopharyngeal carcinoma before treatment.Methods We retrospectively analyzed the blood routine results of 160 cases of nasopharyngeal carcinoma treated by radiotherapy and chemotherapy of nasopharyngeal carcinoma in Cancer Hospital of Anhui Province from December 2015 to October 2017. The clinical stage included in this study was stage Ⅰ in 6 cases,21 cases of stage Ⅱ,62 cases of stage Ⅲ and 71 cases of stage Ⅳ. The levels of WBC,NEUT% and LY% of peripheral blood were detected by Sysmex-XE 5000 hematology analyzer,Monocyte percentage （MONO%） and other indicators,calculate the lymphocyte to neutrophil ratio （LNR）,lymphocyte to monocyte ratio （LMR）. Results There were no significant differences in WBC,NEUTR%,LYR% and LNR between NPC patients and controls （P>0.05）. LNR and LMR of patients with stable nasopharyngeal carcinoma （P<0.05）. Conclusion sThe determination of peripheral blood lymphocyte to neutrophil ratio,lymphocyte to monocyte ratio before treatment in patients with nasopharyngeal carcinoma can be used as evaluation index Pharyngeal cancer patients with progression-free survival and prognosis of useful indicators,

Key words: Nasopharyngeal neoplasms, Lymphocyte to neutrophil ratio, Lymphocyte to monocyte ratio, Prognosis