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临床输血与检验

临床输血与检验 ›› 2016, Vol. 18 ›› Issue (6): 580-582.DOI: 10.3969/j.issn.1671-2587.2016.06.023

• 临床检验 • 上一篇    下一篇

显微镜检查胃液对上消化道出血诊断的临床价值

汪建军,余艳丽,王一丹,刘婧,任超杰   

  1. 712000 咸阳,陕西省核工业215医院检验科
  • 收稿日期:2016-04-12 出版日期:2016-12-20 发布日期:2016-12-23
  • 作者简介:汪建军（1979-）,男,河北承德人,主管技师,硕士,主要从事临床及细胞形态学工作,（E-mail）wangjianjun790319@163.com。

Clinical Significance of the Microscopic Examination of Gastric Juice for Diagnosis of Upper Gastrointestinal Bleeding

WANG Jian-jun, YU Yan-li, WANG Yi-dan, et al   

  1. Department of Clinical Laboratory,Nuclear Industry 215 Hospital of Shan xi Province,Xian yang712000
  • Received:2016-04-12 Online:2016-12-20 Published:2016-12-23

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605

被引次数

3

摘要： 目的采用胃液隐血检测血红蛋白法及转铁蛋白法并与胃液标本显微镜检法进行比较,探讨胃液标本显微镜检查对上消化道出血的诊断价值。方法用两种免疫胶体金法即血红蛋白及转铁蛋白法对临床收集的胃液标本进行检测,同时进行显微镜检查,对所得结果进行统计分析。结果用两种免疫胶体金法及显微镜检法检测的113例胃液标本中,其中经临床确诊消化道出血82例,以临床诊断为标准,胃液潜血血红蛋白法、转铁蛋白法、显微镜检法对消化道出血检测的灵敏度分别为63.4%、64.6%、87.8%,特异度分别为80.6%、71.0%、87.1%,阳性预测值分别为89.6%、85.5%、94.7%,阴性预测值分别为45.5%、43.1%、73.0%,诊断效率分别为68.1%、66.4%、87.6%。与临床诊断进行对比,显微镜检法的差异无统计学意义（P>0.05）,血红蛋白法、转铁蛋白法的差异均有统计学意义（P<0.01）。结论显微镜检法检测胃液对上消化道出血有很好的灵敏度、特异度,对指导临床诊断具有重要的参考价值。

关键词: 胃液隐血, 免疫胶体金法, 显微镜检

Abstract: ObjectiveTo compare the gastric juice occult blood test for hemoglobin and transferrin with microscope examination of specimens of gastric juice,to explore the value of the microscopic examination as an auxiliary method for diagnosis of upper gastrointestinal bleeding. MethodsTwo immune colloidal gold methods of hemoglobin and transferrin were used to test the clinical specimens of the gastric juice and compared with microscopic examination. ResultsEighty two cases of gastrointestinal bleeding,from 113 specimens of gastric juice,were clinically diagnosed.The sensitivity of hemoglobin,transferrin detection methods and microscopy method for gastric juice tests were 63.4%,64.6%and 87.8%,respectively：the specificity of the three methods was 80.6%,71.0% and 87.1%,with the positive predictive value of 89.6%,85.5% and 94.7%,respectively. The negative predictive value was found to be 45.5%,43.1% and 73.0%,with the efficiency of diagnosis of 68.1%,66.4% and 87.6%. No significant statistical difference was noted between the clinical diagnosis and microscopic method. m（P>0.05）.The two immune colloidal gold methods for hemoglobin and transferrin tests,however,were statistically significant（P<0.01）. ConclusionMicroscopic examination of gastric juice presents the promising sensitivity and specificity,and auxiliary diagnostic value for upper gastrointestinal bleeding.

Key words: Occult, blood, of, gastric, juice, Immune, colloidal, gold, method, Microscopic, examination

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