关键词: 红细胞体积分布宽度, 非ST段抬高急性冠状动脉综合征, 心肌肌钙蛋白I

Abstract: ObjectiveTo explore the predictive value of non-ST-segment elevation of acute coronary syndrome（NSTE-ACS）by detection of red blood cell volume distribution width （RDW）for determination of the cut off point. MethodsFrom January 2014 to June 2015,146 NSTE-ACS cases were collected in observation group,and 84 individuals were taken as control with non coronary heart disease confirmed by coronary angiography. The complete blood counting,cardiac troponin I （cTnI）,and blood lipid wee tested. ResultsTC,LDL-C,cTnI,and RDW of NSTE-ACS group was higher than that of the control group,with a higher ratio of high blood pressure history or diabetes history（P<0.05）. The RDW in those with the artery lesions of three branches was higher than with the single artery lesion and double branch lesions（P<0.05）. RDW and cTnI were positively correlated（r=0.298,P<0.05）. RDW receiver operating characteristic（ROC）curve analysis whowed thatthe best cut-off point of RDW for prediction of NSTE-ACS was 11.93%,the area under the ROC curve was 0.845（95% CI：0.792~0.898,P<0.05）,specificity was 82.90%,and sensitivity was 72.62%. Patients with the RDW over 11.93% presented a higher mortality or non-fatal myocardial infarction within 30 days than those with the RDW below 11.93%（P<0.05）. ConclusionRDW is associated with the degree of lesion in NSTE-ACS,and may be used as auxiliary diagnosis and prognosis of NSTE-ACS.

Key words: Red, blood, cell, distribution, width, Non-, ST-segment, elevation, acute, coronary, syndrome, Cardiac, troponin, I