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临床输血与检验 ›› 2018, Vol. 20 ›› Issue (2): 185-188.DOI: 10.3969/j.issn.1671-2587.2018.02.024

• 血型与临床 • 上一篇    下一篇

免疫产生迟发型溶血性输血反应的分析

王丽莉, 杜平   

  1. 830011 乌鲁木齐,新疆医科大学第五附属医院输血科
  • 收稿日期:2017-09-20 出版日期:2018-04-20 发布日期:2018-04-25
  • 通讯作者: 杜平,女,主要从事临床输血与免疫血液学方面的研究,(E-mail )692281637@qq.com。
  • 作者简介:王丽莉(1981-),女,湖南人,主管技师,学士,主要从事输血检验质量管理及免疫血液学工作,(E-mail)27748819@qq.com。

Analysis of Delayed Allogeneic Hemolytic Reaction Following Transfusion

WANG Li-li, DU Ping   

  1. Department of Blood Transfusion,Fifth Affiliated Hospital of Xinjiang Medical University,Urumqi 830011
  • Received:2017-09-20 Online:2018-04-20 Published:2018-04-25

摘要: 目的 通过检测分析患者血型不规则抗体,选择合适的血液进行输注,防止出现迟发型溶血性输血反应,为临床安全输血提供保障。 方法 应用经典抗人球蛋白法对不规则抗体阳性患者的血标本进行抗体鉴定,分析特异性。 结果 在患者血清中检出IgM合并IgG性质抗-E抗体,效价为IgM 32、IgG 128。 结论 在输血前进行不规则抗体筛查,对阳性标本进行抗体鉴定,首次输血的患者在输血前进行Rh抗原分型(CcEe)检测,对保证患者临床输血安全、降低溶血性输血反应具有重要的意义。

关键词: 同种异体反应, 抗体鉴定, Rh抗原分型, 迟发性溶血型输血反应

Abstract: Objective Irregular blood group antibodies were detected in patients to prevent the occurrence of allogeneic delayed hemolytic transfusion reaction (DHTR) and transfusion safety. Methods Classical anti-human globulin test was taken to detect the specific antibodies in the serum of patients. Results The serum titers of IgM and IgG of anti-E were 1∶32 and 1∶128,respectively. Conclusion Rh antigen (CcEe) typing is necessary in the patients who have primary blood transfusion of red blood cells. Screening of irregular antibodies before transfusion is especially important to reduce the reverse reaction of hemolytic transfusion and ensure the clinical blood transfusion safety.

Key words: Immunity, Antibody identification, Rh antigen typing, Delayed hemolytic transfusion, Reaction

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