• 中国科学论文统计源期刊
  • 中国科技核心期刊
  • 美国化学文摘(CA)来源期刊
  • 日本科学技术振兴机构数据库(JST)

临床输血与检验 ›› 2018, Vol. 20 ›› Issue (3): 235-237.DOI: 10.3969/j.issn.1671-2587.2018.03.004

• 单采治疗技术应用专题 • 上一篇    下一篇

治疗性血浆置换术救治高脂血症急性胰腺炎疗效分析*

谈芳,罗娟,滕本秀,李忠俊,冉茜   

  1. 400037 重庆,陆军军医大学第二附属医院
  • 收稿日期:2018-03-22 出版日期:2018-06-20 发布日期:2018-06-22
  • 通讯作者: 冉茜,女,主管技师,助理研究员,博士,主要从事骨髓造血异常发生机制及治疗性输血技术研究,(E-mail)louise-r-q@163.com。
  • 作者简介:谈芳(1990–),女,四川人,护师,主要从事治疗性输血技术研究,(E-mail)465102748@qq.com。
  • 基金资助:
    本课题受国家自然科学基金(No.81372918),国家自然科学青年基金(No.81402634),重庆市杰出青年基金(No.cstc2013jcyjjq10001)资助

Efficacy of Therapeutic Plasma Exchange in Treatment of Acute Hyperlipidemic Pancreatitis

TAN Fang,LUO Juan,TENG Ben-xiu,et al.   

  1. The Second Affiliated Hospital of Army Medical University,Chongqing 400037
  • Received:2018-03-22 Online:2018-06-20 Published:2018-06-22

摘要: 目的 探讨治疗性血浆置换术在高脂血症急性胰腺炎治疗中的应用及疗效。方法 选取本院在2015~2016年住院的16例高脂血症急性胰腺炎患者,予以治疗性血浆置换术治疗,统计患者治疗前后甘油三酯(triacylglyceride,TG)、淀粉酶(amylase,AMY)和脂肪酶(lipase,LPS)的水平。结果 16例高脂急性胰腺炎患者平均置换3次,单次平均置换量2 000 ml。治疗后TG(11.96±5.66 mmol/L vs 3.56±1.06 mmol/L)、AMY(259.14±173.40 IU/L vs 41.71±25.25 IU/L)、LPS(341.92±257.10 IU/L vs 43.5±19.54 IU/L)均下降,差异有统计学意义(P<0.05)。结论 治疗性血浆置换是快速治疗高脂血症急性胰腺炎的有效手段。

关键词: 高脂血症, 急性胰腺炎, 治疗性血浆置换术

Abstract: Objective To investigate the therapeutic effect of plasmapheresis in treatment of acute hyperlipidemic pancreatitis (AHP). Methods A total of 16 AHP patients in the hospital between 2015 and 2016 were collected and treated with therapeutic plasmapheresis. The levels of triglyceride (TG),amylase (AMY) and lipase (LPS) before and after treatments were examined. Results Sixteen AHP patients who received plasmapheresis with the average of 3 treatments,2000 mL for each,showed significant decreases in TG (11.96±5.66 mmol/L vs 3.56±1.06 mmol/L),AMY (259.14±173.40 IU/L vs 41.71 ±25.25 IU/L),and LPS (341.92±257.10 IU/L vs 43.5±19.54 IU/L) (P<0.05). Conclusion Therapeutic plasma exchange is an effective method for treatment of acute hyperlipidemic pancreatitis.

Key words: Hyperlipidemia, Acute pancreatitis, Therapeutic plasma exchange

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