未成熟血小板计数在机采血小板质量评价中的作用*

doi:10.3969/j.issn.1671-2587.2018.05.002

临床输血与检验 ›› 2018, Vol. 20 ›› Issue (5): 453-456.DOI: 10.3969/j.issn.1671-2587.2018.05.002

未成熟血小板计数在机采血小板质量评价中的作用^*

黄慧珊, 郑桂安, 张琳

363000 福建省漳州市中心血站（黄慧珊）;
福建医科大学附属漳州市医院内科（郑桂安）;
武汉大学人民医院产科（张琳）

收稿日期:2018-03-25 出版日期:2018-10-20 发布日期:2018-09-27
通讯作者: 郑桂安,男,博士,副主任医师,（E-mail） zga@fjmu.edu.cn。
作者简介:黄慧珊（1981-）,女,福建漳州人,主管检验师,学士,主要从事血液检验工作,（E-mail） 42086352@qq.com。
基金资助:
*本课题受福建省自然科学基金项目（No.2016J01486）资助

Immature Platelet Count as a Novel Quality Marker in Plateletpheresis

HUANG Hui-shan, ZHENG Gui-an, ZHANG Lin

Zhangzhou Blood Center,Zhangzhou 363000

Received:2018-03-25 Online:2018-10-20 Published:2018-09-27

摘要/Abstract

摘要： 目的分析献血者和受血者的血小板相关指标,探讨能较好评价机采血小板质量的指标。方法选择2015年6月~2016年12月漳州市中心血站采集的104例机采血小板,应用Sysmex XN-1000全自动血细胞分析仪,对献血者和受血者输血前后的血小板相关指标进行分析。结果输注1 U和2 U机采血小板的受血者,其输血前的未成熟血小板计数（IPC）与输血后1 h（P_1单位<0.001,P_2单位<0.001）、输血后24 h（P_1单位=0.015,P_2单位<0.001）的IPC相比,差异均有统计学意义。献血者IPC与受血者输血前后1 h IPC的百分比变化、受血者输血前后24 h IPC的百分比变化均呈正相关（r_1h=0.536,P_1h<0.001;r_24h=0.413,P_24h<0.001）。结论未成熟血小板计数能较好地评估机采血小板质量,可用于献血者筛选和受血者输血后的随访。

关键词: 未成熟血小板计数, 机采血小板, 质量指标

Abstract: Objective To explore better quality parameters for valuation of plateletpheresis,we investigate the platelets parameters of donors and recipients.Methods One hundred and four apheresis platelet collected in Zhangzhou Blood Center from June 2015 to December 2016. Platelets parameters of donors and recipients before and after transfusion were analyzed by Sysmex XN-1000 automated blood cell counter. Results For recipients of single and double unit apheresis platelet transfusions,there is a significant difference among the pretransfusion and 1st hour immature platelet count （IPC）（P_single-unit<0.001,P_double-unit<0.001）,and 24th hour IPC （P_single-unit=0.015,P_double-unit<0.001）. There is a positive correlation between donor IPC and the percent change between pretransfusion and 1st hour after transfusion of recipient（r=0.536,P<0.001）,and percent change between pretransfusion and 24th hour after transfusion of recipient（r=0.413,P<0.001）. Conclusion IPC can be used to determine the quality of plateletpheresis in terms of evaluation of donors and also in the follow up of recipients undergoing platelet transfusion.

Key words: Immmature platelet count, Plateletpheresis, Quality parameters

中图分类号:

R331.1⁺43

黄慧珊, 郑桂安, 张琳. 未成熟血小板计数在机采血小板质量评价中的作用^*[J]. 临床输血与检验, 2018, 20(5): 453-456.

HUANG Hui-shan, ZHENG Gui-an, ZHANG Lin. Immature Platelet Count as a Novel Quality Marker in Plateletpheresis[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2018, 20(5): 453-456.

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未成熟血小板计数在机采血小板质量评价中的作用^*

Immature Platelet Count as a Novel Quality Marker in Plateletpheresis

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