• 中国科学论文统计源期刊
  • 中国科技核心期刊
  • 美国化学文摘(CA)来源期刊
  • 日本科学技术振兴机构数据库(JST)

临床输血与检验 ›› 2019, Vol. 21 ›› Issue (4): 341-344.DOI: 10.3969/j.issn.1671-2587.2019.04.002

• 临床输血 • 上一篇    下一篇

造血干细胞移植患者红细胞输血效果的影响因素分析*

马春娅, 孙晓琳, 封彦楠, 张晓娟, 姜旭, 于洋, 汪德清   

  1. 100853 北京,解放军总医院输血科
  • 收稿日期:2018-10-12 出版日期:2019-08-20 发布日期:2019-08-28
  • 通讯作者: 汪德清,教授,博士生导师,主要从事临床输血风险控制研究,(E-mail)deqingw@vip.sina.com。
  • 作者简介:马春娅(1981-),女,河北人,主管技师,硕士,主要从事临床输血研究,(E-mail)mcydou@163.com。
  • 基金资助:
    *本课题受解放军总医院医疗大数据研发项目(No.2016MBD-023)资助

Analysis of Influence Factors of Erythrocyte Transfusion in Patients with Hematopoietic Stem Cell Transplantation

MA Chun-ya, SUN Xiao-lin, FENG yan-nan, et al   

  1. Department of Blood Transfusion, The PLA General Hospital, Beijing 100853
  • Received:2018-10-12 Online:2019-08-20 Published:2019-08-28

摘要: 目的 分析造血干细胞移植患者红细胞输血效果的影响因素,提高输血效果。方法 通过临床输血管理系统,回顾性分析2016年1~12月造血干细胞移植患者输血前后基本信息及血液信息,以红细胞输注前后血红蛋白变化为因变量,其他调查指标为自变量,应用多因素线性回归模型,计算红细胞输血效果的影响因素。结果 89例造血干细胞移植患者,共输注红细胞409次,影响红细胞输血效果的因素包括患者输血前脉搏、身高、体重、单次红细胞输血量、红细胞保存天数。结论 造血干细胞移植患者应尽量选择保存天数较短的红细胞输注,对处于血型转型期的患者,应根据具体血清学格局制定个体化的输血策略输注红细胞。

关键词: 造血干细胞移植, 红细胞输血, 输血效果, ABO血型

Abstract: Objective To analyze the influencing factors of red blood cell transfusion in patients with hematopoietic stem cell transplantation so as to improve the efficacy of blood transfusion. Methods The fundamental information before and after transfusion in patients who had underwent hematopoietic stem cell transplantation were retrospectively analyzed from January 2016 to December 2016. The changes in hemoglobin were used as the dependent variables whereas other indicators, as independent variables. The model of multi-factor linear regression analysis was used to calculate the influencing factors of transfusion. Results A total of 409 person-times of transfusions were performed in 89 patients with hematopoietic stem cell transplantation. The heart rate, height, weight, volume of single transfusion, and days of blood preservation were considered as influencing factors. Conclusion Patients with hematopoietic stem cell transplantation benefit from the blood with fresh preservation. For patients in the blood group transition stage, individual strategy should include the blood according to specific serological patterns.

Key words: Hematopoietic stem cell transplantation, Red blood cell transfusion, Effect of blood transfusion, ABO blood group

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