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临床输血与检验

临床输血与检验 ›› 2020, Vol. 22 ›› Issue (2): 131-134.DOI: 10.3969/j.issn.1671-2587.2020.02.005

• 临床输血 • 上一篇    下一篇

深度自体储血技术在特发性脊柱侧弯矫形术中的应用研究

王瑞含, 彭娟, 刘久波   

  1. 442000 十堰市太和医院输血科
  • 收稿日期:2019-08-02 出版日期:2020-04-20 发布日期:2020-04-16
  • 通讯作者: 刘久波,男,主任医师,教授（E-mail）ljb169168@sina.com。
  • 作者简介:王瑞含（1994-）,女,山东菏泽人,医师,在读硕士研究生,主要从事临床检验诊断学方面研究,（Tel）15871110108（E-mail）952017575@qq.com。

Study on the Application of Advanced Autologous Apheresis in Idiopathic Scoliosis

WANG Rui-han, PENG Juan, LIU Jiu-bo   

  1. Department of Blood Transfusion, Taihe Hospital, Shiyan City, Hubei 442000
  • Received:2019-08-02 Online:2020-04-20 Published:2020-04-16

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摘要： 目的 探讨深度自体储血技术(advanced autologous apheresis,AAA) 在特发性脊柱侧弯矫形术中避免异体血输注的临床效果。方法 统计某三甲医院2018年7月~2019年7月行特发性脊柱侧弯择期手术的32例患者,根据是否进行AAA分为AAA组和对照组,比较两组患者的一般临床资料,术前3天、入手术室时、术后1天、术后3天的红细胞（RBC）、血红蛋白（Hb）、红细胞压积（HCT）、血小板（PLT）水平,自体血采集量及术中异体红细胞、血浆的输注量。结果 两组患者一般临床资料、手术资料及术前3天RBC、Hb、HCT、PLT水平差异无统计学意义（P均>0.05）;AAA组较对照组自体血储存量明显增加（P<0.05）,异体红细胞使用量明显减少（P<0.05）;AAA组患者在储血后较储血前RBC、Hb、HCT水平降低（P均<0.05）,PLT水平无明显差异（P>0.05）;两组间术后RBC、Hb、HCT、PLT水平差异均无统计学意义（P均>0.05）。结论 深度自体储血技术可在短时间内单采大量自体浓缩红细胞,可减少特发性脊柱侧弯矫正术患者异体血的使用。

关键词: 深度自体储血技术, 单采自体红细胞, 特发性脊柱侧弯

Abstract: Objective Toevaluate the clinical effect of advanced autologous apheresis （AAA） in avoiding allogeneic blood transfusion in idiopathic scoliosis surgery. Methods We reviewed 32 idiopathic scoliosis patients who underwent elective surgery at a single hospital from July 2017 to July 2018. The patients were divided into AAA group and control group. We compared general information, surgical characteristics, autologous red blood cells （RBC） collecting amount, allogeneic RBC and plasma transfusion volume, laboratory data including RBC count, hemoglobin （Hb） level, hemotocrit （HCT）, platelet count （PLT） in preoperative 3 days, operating time, postoperative 1 day and 3 days. Results Two cohorts had no differences in general information, surgical characteristics and preoperative levels of RBC, Hb, HCT and PLT （P>0.05）. Compared to control group, autologous blood collecting amount in AAA group was much higher（P<0.05）, and allogeneic RBC transfusion volume was significantly reduced（P<0.05）. After autologous blood collecting, RBC, Hb and HCT levels of patients were lower than before（P<0.05）, and no decline in PLT levels（P>0.05）. Two cohorts had no differences in postoperative in RBC, Hb, HCT and PLT levels（P>0.05）. Conclusion AAA can reduce allogeneic transfusion in idiopathic scoliosis patients.

Key words: Advanced Autologous, Apheresis, Erythrocyte Apheresis Idiopathic Scoliosis

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