全血献血者献血相关迷走神经反应影响因素的系统评价及Meta分析

doi:10.3969/j.issn.1671-2587.2025.03.017

临床输血与检验 ›› 2025, Vol. 27 ›› Issue (3): 384-392.DOI: 10.3969/j.issn.1671-2587.2025.03.017

全血献血者献血相关迷走神经反应影响因素的系统评价及Meta分析

王静^1,2, 武凯¹, 孙志芳^2,3, 王梦璇¹, 郭荣¹, 麻春英^4,5

¹乌鲁木齐市血液中心 830000;
²新疆医科大学护理学院 830011;
³新疆维吾尔自治区人民医院克拉玛依医院 834000;
⁴新疆维吾尔自治区人民医院 830001;
⁵新疆区域人群疾病与健康照护研究中心 830001

收稿日期:2024-02-26 发布日期:2025-06-23
通讯作者: 麻春英,主要从事临床护理及其相关研究,（E-mail）wangjing4002@163.com。
作者简介:王静,主要从事护理及其相关研究,（E-mail）375334995@qq.com。

Influence Factors of Donation Related Vasovagal Reactions in Whole Blood Donors: A Systematic Review and Meta-analysis

WANG Jing^1,2, WU Kai¹, SUN Zhifang^2,3, WANG Mengxuan¹, GUO Rong¹, MA Chunying^4,5

¹Urumqi Blood Center, Urumqi 830000;
²School of Nursing of Xin Jiang Medical University, Urumqi 830011;
³Karamay Hospital of Xinjiang Uygur Autonomous Region, Karamay 834000;
⁴People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001;
⁵Health Care Research Center for Xinjiang Regional population, Urumqi 830001

Received:2024-02-26 Published:2025-06-23

摘要/Abstract

摘要： 目的系统评价全血献血者发生献血相关迷走神经反应（DRVR）的风险因素。方法通过计算机检索PubMed、Web of Science等数据库,以获取关于全血献血者发生DRVR风险因素的研究数据,通过 RevMan5.4软件来执行Meta分析的数据。结果共保留了24篇相关文献,涉及62 623例DRVR的献血者,Meta分析结果揭示,对于献血者来说,首次献血、女性、年龄<25岁、BMI<18.5、体重<55 kg、脉搏>90次/分钟、血容量<3.5 L、恐惧情绪、动员献血、吃饭后时间>4 h是导致DRVR发生的风险因素。结论献血者DRVR的发生存在多种危险因素,应针对危险因素评估和筛查高危献血者,及时采取预防护理措施以降低DRVR的发生率。

关键词: 献血者, 献血相关迷走神经反应, 风险因素, Meta分析

Abstract: Objective To systematically analyze the risk factors of donation related vasovagal reaction (DRVR) in whole blood donors. Methods This study utilized databases such as PubMed and Web of Science to retrieve research data on the risk factors of DRVR in whole blood donors. Meta-analysis was done using RevMan5.4 software to process the data. Results A total of 24 relevant studies were in the analysis, involving 62 623 blood donors with DRVR. Meta-analysis revealed that first-time donors, female gender, age<25 years old, BMI<18.5, weight<55 kg, pulse rate > 90/min, estimated blood volume<3.5 L, fear emotion, recruitment blood donation and time after eating>4 h were significant risk factors for DRVR. Conclusion There are numerous risk factors for DRVR in blood donors. High risk population should be evaluated and screened in light of these factors, and timely interventions and nursing measures should be implemented to reduce the incidence of DRVR.

Key words: Blood donors, Donation related vasovagal reaction, Risk factors, Meta-analysis

中图分类号:

R457

王静, 武凯, 孙志芳, 王梦璇, 郭荣, 麻春英. 全血献血者献血相关迷走神经反应影响因素的系统评价及Meta分析[J]. 临床输血与检验, 2025, 27(3): 384-392.

WANG Jing, WU Kai, SUN Zhifang, WANG Mengxuan, GUO Rong, MA Chunying. Influence Factors of Donation Related Vasovagal Reactions in Whole Blood Donors: A Systematic Review and Meta-analysis[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2025, 27(3): 384-392.

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全血献血者献血相关迷走神经反应影响因素的系统评价及Meta分析

Influence Factors of Donation Related Vasovagal Reactions in Whole Blood Donors: A Systematic Review and Meta-analysis

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