CRP/PA比值对慢阻肺急性加重期的临床价值

doi:10.3969/j.issn.1671-2587.2019.02.027

临床输血与检验 ›› 2019, Vol. 21 ›› Issue (2): 205-208.DOI: 10.3969/j.issn.1671-2587.2019.02.027

CRP/PA比值对慢阻肺急性加重期的临床价值

赵睿

243000 安徽省马鞍山市中心医院

收稿日期:2018-12-07 出版日期:2019-04-20 发布日期:2019-04-10
作者简介:赵睿（1979-）,女,安徽马鞍山人,主治医师,学士,主要从事呼吸内科常规诊疗工作,（Tel）13955537976。

The Clinical Value of CRP/PA Ratio in the Acute Exacerbation of Chronic Obstructive Pulmonary Disease

ZHAO Rui

Central Hospital of Ma'anshan,Anhui,243000

Received:2018-12-07 Online:2019-04-20 Published:2019-04-10

摘要/Abstract

摘要： 目的探讨血清C-反应蛋白（CRP）、前白蛋白（PA）指标水平变化对慢阻肺疾病早期临床诊断的价值。方法选取2015年3月~2016年3月马鞍山市中心医院呼吸内科的COPD急性加重期患者50例为研究组,稳定期COPD患者50例为对照组,观察治疗前后CRP、PA、RDW、WBC、N%等指标变化,并计算血清CRP和PA比值。结果治疗前研究组的CRP水平高于治疗后和对照组,治疗后CRP水平仍高于对照组（P<0.05）;研究组治疗前PA值明显低于治疗后和对照组,治疗后仍对低于照组（P<0.05）;CRP和PA比值0.853明显高于0.1;研究组治疗前阳性检出率CRP(84%)、PA（76%）、WBC（26%）、RDW(62%)、N%(72%)均显于治疗后及对照组（P<0.01）。结论 CRP/PA比值对于早期诊断AECOPD具有重要的指导意义,给临床应用抗生素提供有力的医学证据。

关键词: 慢性肺疾病, 急性加重期, 比值, 阳性检出率

Abstract: Objective To explore the value of CRP/PA ratio in the early clinical diagnosis and treatment of chronic obstructive pulmonary disease. Method sCRP,PA,RDW,WBC,N% and other indicators were detected before and after treatment,as well as serum C-reactive protein (CRP) and prealbumin (PA ratio) in COPD of 50 patients with acute exacerbation of patients with stable COPD group,50 cases in the control group in the Ma'anshan Market Center Hospital from March 2015 to March 2016. Results CRP was significantly higher in the study group before treatment than that in the control group after treatment,CRP is still higher than the control group after treatment (P<0.05); the study group before treatment was significantly lower PA than that of after treatment and control group after treatment control group (P<0.05); C-reactive protein (CRP) and prealbumin (PA) ratio of 0.853 the study group before treatment; the positive rate of CRP (84%),PA (76%),WBC (26%),RDW (62%),N% (72%) was significantly higher than that after treatment and control group (P<0.01). Conclusion CRP/PA ratio has an important guiding significance for the early diagnosis of AECOPD,which provides strong evidence for effective medical clinical application of antibiotics.

Key words: Chronic lung disease, Acute exacerbation, Ratio, Positive detection rate

中图分类号:

R563R446.11

赵睿. CRP/PA比值对慢阻肺急性加重期的临床价值[J]. 临床输血与检验, 2019, 21(2): 205-208.

ZHAO Rui. The Clinical Value of CRP/PA Ratio in the Acute Exacerbation of Chronic Obstructive Pulmonary Disease[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2019, 21(2): 205-208.

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CRP/PA比值对慢阻肺急性加重期的临床价值

The Clinical Value of CRP/PA Ratio in the Acute Exacerbation of Chronic Obstructive Pulmonary Disease

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