Abstract: Objective To understand reticulated platelet level changes in apheresis platelet donors. Methods The platelets donators were divided into experimental group (A) and control group(B). Group A comprised 153 cases of apheresis platelet donors and group B included 189 cases without the experience of blood donation. Automated blood analyzer was used for testing WBC,RBC,Hb,HCT,PLT,PDW,PCT,MPV and IPF proportions and other items. Results No significant difference was seen of WBC and PCT（P>0.05） in the male blood donors in Group A,whereas RBC,Hb,HCT,and PLT were obviously elavated（P<0.05）and PDW, MPV,and IPF decreased（P<0.05）. Comparatively, WBC,RBC,Hb,HCT,PLT,PCT,and MPV did not give rise to any change in female donors（P>0.05）whereas PDW and IPF were significantly increased（P<0.05）. Conclusion Repeated apheresis platelet donations may accelerate RBC and PLT rather than IPF production in bone marrow,and promote the PLT maturity. Female donors, due to the periodic blood loss of RBC,may have a higher capacity of platelets generation capacity than males.

Key words: Reticulated platelets, Apheresis platelets, Bone marrow