Abstract: Objective To compare the application effects of acute normovolemic hemodilution（ANH） and acute hypervolemic hemodilution （AHH） in ectopic pregnancy surgery. Methods 96 cases of surgical patients with ectopic pregnancy were randomly divided into ANH group,AHH group and control group,32 cases in each group. The patients in ANH group were received ANH after anesthesia induction and before the operation,the patients in AHH group were received AHH after anesthesia induction and before the operation,the patients in control group were not received acute hemodilution before the operation,the compound sodium lactate injection was infused after anesthesia induction and before the operation. The indicators such as Hb,Hct,BE,LAC were compared before and after acute hemodilution in ANH group and AHH group. Mean arterial pressure （MAP）,heart rate（HR）,cardiac index （CI） and stroke volume variation rate （SVV） at different time points were compared in ANH group and AHH group. The levels of Hb,Hct,PLT and cases of allogeneic blood transfusion were compared after the operation in three groups. Results ①The indicators such as Hb,Hct,BE,LAC were no statistical differences（P>0.05）before and after acute hemodilution in ANH group and AHH group. ② MAP,CI before and after autologous blood transfusion in ANH group was higher than those in AHH group（P<0.05）,and SVV was lower than that in AHH group（P<0.05）.③The levels of Hb、Hct、PLT at 2 h after the operation in ANH group were higher than those in AHH group and control group（P<0.05）,the cases and volumes of allogeneic blood transfusion in ANH group were less than those in AHH group and control group（P<0.05）. The cases and volumes of allogeneic blood transfusion in AHH group were less than those in control group（P<0.05）. Conclusion ANH can effectively reduce the loss of red blood cells in ectopic pregnancy surgery and reduce allogeneic blood transfusion,has less influence on hemodynamics,safety performance is good,has a certain clinical value.

Key words: Acute normovolemic hemodilution, Acute hypervolemic hemodilution, Ectopic pregnancy, Surgery