Abstract: Objective we summarized early clinical characteristics of infants with Kawasaki disease,including clinical manifestations and laboratory examinations,in order to impove early-diagnosis. Methods Retrospective data from 21 cases of KD in infants was analysed,compared with 20 cases of KD in children older than 1 year in the same period. Results Compared with 20 cases of KD in children older than 1 year,the incidence of some clinical features,such as BCG vaccination erythrocyte,symptoms in digestive system and nervous system at early period were significantly（P<0.05）,while cervical lymphadenopathy was absent in 21 cases of KD in infants. The incidence of IKD cases in infants increased statistically（P<0.05）,Laboratory results,such as PLT,and the level of CRP,ALB,CK-MB have no difference except WBC and Hb. The cases of KD in infants have higher in WBC,but lower in Hb （P<0.05）.More cases of KD with hepatic injury or coronary artery aneurysm appear in infants（P<0.05）. Conclusion IKD cases and coronary artery aneurysm are more common in infants with KD.Not only the manual clinical features,but also BCG vaccination erythrocyte,symptoms in digestive system and nervous system and the level of WBC,Hb,PLT,CRP,ESR,ALT in time would be provide a clue for early diagnosis.Then completing the examination of coronary artery at the right time is necessary.

Key words: Infant, Kawasaki disease, Clinical manifestation, Hematology characteristic