Abstract: Objective To evaluate the performance of TOSOH HLC-723 G8 analyzer for clinical detection of HbA_1C. Method sPrecision verification was based on EP15-A2 and WS/T461-2015 methods. Correctness verification was compared with the results of Bio-Rad D10 reference detection system. The WS/T420-2013 verification method was used for linear verification,and the carrying rate was three times with high and low values of continuous sampling. Results The low value of short term precision was 0.86% and the high value,0.98%. The long-term precision low value was 0.98% and the high value,0.69%,which is highly correlated to the results tested by the reference instrument （r=0.999,r²=0.998,P=0.000）. Additionally,a good linearity in the range of 5.2% and 15.2% （y=1.0115x-0.0505,r=0.9997） and low rate of carryover（k=1.00%） were noted. Conclusion TOSOH HLC-723 G8 has a high precision,good linearity and low pollution rate and can be used for clinical detection of HbA_1C.

Key words: Glycohemoglobin, Performance, evaluation, Clinical, examination, diagnosis