Abstract: Objective To analyze the correlation between the ratio of neutrophil lymphocytes in peripheral blood and the effect of blood transfusion in patients with traumatic blood loss. Methods This was a retrospective analysis of 568 traumatic blood loss patients admitted to our hospital from January 2017 to December 2019, which were divided into effective group (n=500) and ineffective group (n=68) according to the effect of blood transfusion. The general information such as age and gender of the two groups of patients, and the commonly used laboratory indicators such as hemoglobin (Hb), Neutrophil lymphocyte ratio (NLR) and so on were compared. Multi-factor Logistic regression was used to analyze the above factors, and the receiver operating characteristic curve (ROC curve) was used to analyze the diagnostic value of related factors to predict the efficacy of transfusion. Results The age, ISS score and NLR level of the patients in the effective group were significantly lower than those in the ineffective group. The levels of SBP, DBP, respiratory rate, GCS score, Hb, PLT and APTT were significantly higher than those in the ineffective group (all P<0.05); There were no significant difference among the patients' gender, trauma type, and other factors (all P>0.05); multivariate logistic analysis showed high GCS values (OR=0.804, 95% CI: 0.707-0.913) and high Hb (OR=0.937, 95% CI: 0.908-0.967), PLT level (OR=0.984, 95% CI: 0.976-0.992) were protective factors affecting the efficacy of transfusion, while high ISS value (OR=1.288, 95% CI: 1.128-1.471), high NLR (OR=4.434, 95% CI: 2.905-6.766) and APTT level (OR=1.087,95% CI: 1.033-1.145) were independent risk factors affecting the efficacy of blood transfusion; ROC curve showed that the diagnostic efficacy of NLR was significantly higher than that of GCS, ISS, Hb, APTT, and PLT (Z=3.627, 3.487, 2.860, 3.903, 3.030; all P<0.05). The optimal cut-off point for NLR diagnosis was 4.41. At this time, the sensitivity was 86.8% and the specificity was 67.0%. Conclusion NLR was a highly valuable predictor of transfusion efficacy in patients with traumatic blood loss.

Key words: Neutrophil lymphocyte percentage value, Traumatic hemorrhage, Transfusion effect, Correlation analysis