The Past, Present and Prospect of Whole Blood Transfusion

doi:10.3969/j.issn.1671-2587.2024.04.022

JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2024, Vol. 26 ›› Issue (4): 563-569.DOI: 10.3969/j.issn.1671-2587.2024.04.022

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The Past, Present and Prospect of Whole Blood Transfusion

ZHANG Lingling, LIU Erxiong, LIU Zhixin, AN Qunxing, YIN Wen

Department of Transfusion Medicine, the First Affiliated Hospital of Air Force Military Medical University, Xi'an 710032

Received:2024-07-07 Online:2024-08-20 Published:2024-09-23

Abstract

Abstract: Whole blood was the earliest blood product ever used, however, with the advent of component transfusion treatments, whole blood all but disappeared from blood bank lists in the 1970 s. In recent years, based upon the successful military experience, the use of whole blood to resuscitate patients with hemorrhagic trauma has again attracted the attention of the blood transfusion circle,and it has gradually been introduced from the military field to the civilian treatment settings.Based on the guidelines for whole blood transfusion at home and abroad and related published studies, this paper reviews the classification of whole blood, history of whole blood use, whole blood storage and platelet protection, removal of whole blood white blood cells, inactivation of whole blood pathogens, and urgent problems to be solved in scientific and accurate transfusion of whole blood, and looks forward to its future development direction, providing reference for the introduction of whole blood more widely, and the development of blood transfusion medicine.

Key words: Whole blood, Low titer O whole blood, Whole blood transfusion

CLC Number:

R457.1

ZHANG Lingling, LIU Erxiong, LIU Zhixin, AN Qunxing, YIN Wen. The Past, Present and Prospect of Whole Blood Transfusion[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2024, 26(4): 563-569.

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