Abstract: Objective Effects of red blood cell distribution width,Cys-C secondary pulmonary hypertension in patients with chronic obstructive pulmonary disease and its severity of predictive value. Method From our hospital in 2012 during the April to June 2015 were selected in patients with chronic obstructive pulmonary disease into standard patient 108 cases,and divided into the normal pulmonary artery pressure group （84 cases） and the increased pulmonary artery pressure group （24 cases）. Observe the red blood cell distribution width （RDW） and Cys-C and other indicators are analyzed. Result The red blood cell distribution width （RDW） value in the increased pulmonary artery pressure group [（15.19±1.69） %] was significantly higher than in the normal group [（14.38±1.42）%] （P<0.01）; the Cys-C value in the increased pulmonary artery pressure group [（1.32±0.41）] was significantly higher than in the normal group [（0.95±0.46）] （P<0.01）. RDW,Cys-C and pulmonary hypertension were positive correlation and the difference were statistically significant （P<0.01）. Conclusion Red blood cell distribution width （RDW） and Cys-C values are secondary pulmonary hypertension in copd patients have obviously increased,are positively correlated with pulmonary hypertension severity. Red blood cell distribution width and Cys-C also to predict chronic obstructive pulmonary disease severity of secondary pulmonary hypertension has important clinical value,is a reliable predictor for the disorder.

Key words: Red blood cell distribution width, Cys-C, Chronic obstructive pulmonary disease, Correlation analysis, Pulmonary arterial hypertension