Abstract: With the development of blood transfusion medicine, more and more attention has been paid to the health of donors. In order to monitor the adverse reactions of blood donors, many countries and regions have formulated the vigilance standards for the adverse reactions of blood donation. They have carried out the vigilance of the adverse reactions of blood donation systematically, and studied the incidence rate and occurrence mechanism for the prevention and disposal of the adverse reactions of blood donation. In our review, we summarized vigilance standards, data access, incidence of adverse reactions, the related factors and the influence of blood donation adverse reaction and analyzed the measures of prevention and treatment of adverse reactions. It provides scientific basis for the blood collecting and supplying institutions and related departments to understand the adverse reactions of blood donation and carry out related prevention and control adverse reactions of blood donation.

Key words: Adverse reactions to blood donation, Heamovigilance, Donor safety