Correlation Study of Gender, Age, and ABO Blood Group with Platelet Counts

doi:10.3969/j.issn.1671-2587.2026.04.022

JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2026, Vol. 28 ›› Issue (4): 608-613.DOI: 10.3969/j.issn.1671-2587.2026.04.022

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Correlation Study of Gender, Age, and ABO Blood Group with Platelet Counts

ZHOU Shihang, LIU Jiandi, SONG Wenqian, FAN Yaxin

Dalian Blood Center, Dalian 116001

Received:2026-07-06 Online:2026-08-20 Published:2026-08-26

Abstract

Abstract: Objective This study is to assess associations of sex, age, and ABO blood group with platelet counts. Methods A total of 4 657 healthy donors were enrolled. ABO groups were determined serologically and platelet counts measured by automated hematology analyzer. Associations were evaluated using R software (4.4.1). Results Mean platelet count was lower in males [(243±45.3)×10⁹/L] than that in females [(259±50.2)×10⁹/L] (t=-10.15, P<0.001). Age correlated negatively with platelet count in both sexes (male: r=-0.13, female: r=-0.14; both P<0.001). Age-stratified trend analysis showed an overall decline with age; males exhibited a steady gradual decrease, while females remained relatively stable between ages 30~49. Multivariable linear regression identified sex, age, and ABO group as independent predictors; group B had lower platelet counts than group A (P<0.05). Conclusion Platelet counts are lower in males than in females. Platelet counts decline slowly with age, with a relatively stable phase in females. ABO blood group is associated with platelet count; it may be a heritable trait affecting platelet count.

Key words: Sex, Age, ABO blood group, Platelet count

CLC Number:

R446.11

ZHOU Shihang, LIU Jiandi, SONG Wenqian, FAN Yaxin. Correlation Study of Gender, Age, and ABO Blood Group with Platelet Counts[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2026, 28(4): 608-613.

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Correlation Study of Gender, Age, and ABO Blood Group with Platelet Counts

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