Abstract: ObjectiveTo explore the clinical value in combined detection of the serum tumor markers on patients with hepatocellular carcinoma. Methods56 cases primary liver cancer of the hospitalized patients, 32 cases of other liver diseases, and 34 healthy persons were collected. Carcinoembryonic antigen (CEA), serum malignant tumor growth factor (TSGF), glutamate based transpeptidase (GGT), alpha fetoprotein (AFP) and fucosidase (AFU) were determined. ResultsIndexes AFP, TSGF, AFU, GGT and CEA in patients with primary liver cancer were higher than those with benign liver diseases and normal control (P<0.05). The sensitivity and specificity of combined detection were higher than those of the single test (P <0.05). ConclusionThe combined detection of serum tumor markers of liver cancer can effectively improve the accuracy of diagnosis, and provide important basis for the differential diagnosis of hepatocellular carcinoma.

Key words: Serum, tumor, marker, Liver, cancer, Diagnosis, Detection